Saense e ka morao ho N-Acetylcysteine: Kamoo e Tšehetsang Mosebetsi oa ho Phefumoloha

N-Acetylcysteine ​​powder, eo hape e tsejoang e le NAC, ke antioxidant e matla ebile e le selelekela sa glutathione, molek'hule ea bohlokoa tšireletsong ea 'mele ea rona khahlano le lintho tse chefo. Le hoja NAC e 'nile ea sebelisoa ka lilemo tse mashome e le moemeli oa mucolytic, lipatlisiso tsa morao-rao li fane ka leseli mabapi le karolo ea eona ea ho tšehetsa mosebetsi oa phefumoloho. Sehloohong sena, re tla hlahloba saense ka morao ho N-Acetylcysteine ​​​​le liphello tsa eona tse molemo tsamaisong ea ho hema.

Ho utloisisa hore na N-Acetylcysteine ​​​​e tšehetsa mosebetsi oa phefumoloho joang, re tlameha ho hlahloba mekhoa ea motheo ea bophelo bo botle ba phefumoloho. Mokhoa oa ho hema o akarelletsa litsela tsa rōna tsa moea, matšoafo le marang-rang a rarahaneng a lisele tse ikarabellang bakeng sa phapanyetsano ea khase. Leha ho le joalo, ho pepesehela lintho tse silafatsang, likokoana-hloko, kapa maemo a itseng a bongaka ho ka lebisa khatellong ea oxidative le ho ruruha, ho senya mosebetsi oa ho hema.

Mona ke moo N-Acetylcysteine ​​​​e ipakang e le ea bohlokoa. E le selelekela sa glutathione, e sebetsa e le antioxidant e matla, e fokotsang li-radicals tse kotsi le ho fokotsa khatello ea oxidative. Ka ho tlatsa maemo a intracellular glutathione, N-Acetylcysteine ​​​​e thusa ho boloka botsitso bo bobebe ba li-antioxidants le ho sireletsa tsamaiso ea phefumoloho hore e se ke ea senyeha.

Ho feta moo, N-Acetylcysteine ​​​​e na le thepa ea mucolytic, ho bolelang hore e thusa ho senya le ho tšesaane ho mucus moeeng. Sena se molemo ka ho khetheha ho batho ba nang le maemo a sa foleng a phefumoloho, a kang chronic obstructive pulmonary disease (COPD) kapa cystic fibrosis, moo tlhahiso e feteletseng ea mucus le ho senyeha ha tumello ho ka sitisang moea. Ka ho khothalletsa ho tlosoa ha mucus, N-Acetylcysteine ​​​​e ntlafatsa ts'ebetso ea matšoafo le ho fokotsa kotsi ea mathata a ho hema.

Liphuputso tse 'maloa tsa saense li tiisitse liphello tse molemo tsa N-Acetylcysteine ​​​​ho bophelo bo botle ba phefumoloho. Mohlala, phuputso e phatlalalitsoeng ho European Respiratory Journal e bontšitse hore tlatsetso ea N-Acetylcysteine ​​​​e ntlafalitse tšebetso ea matšoafo le ho fokotsa ho mpefala ha phefumoloho ho batho ba nang le COPD. Phuputso e 'ngoe e hatisitsoeng ho American Journal of Respiratory and Critical Care Medicine e fumane hore N-Acetylcysteine ​​​​e fokolitse khafetsa le ho teba ha litlhaselo tsa asthma ho bana.

Ka ntle ho thepa ea eona ea antioxidant le mucolytic, N-Acetylcysteine ​​​​e boetse e bontša liphello tse khahlanong le ho ruruha. Ho ruruha ke letšoao la mafu a ho hema, kaha ho tlatsetsa ho thibela moea le ho senyeha ha lisele. N-Acetylcysteine ​​​​e thusa ho laola ho lokolloa ha limolek'hule tsa pro-inflammatory, tse kang cytokines, le ho fetola karabelo ea 'mele ea ho itšireletsa mafung. Ka ho fokotsa ho ruruha ha cascade, N-Acetylcysteine ​​​​e kokobetsa matšoao a ho hema 'me e khothalletsa ho hlaphoheloa.

Ke habohlokoa ho hlokomela hore N-Acetylcysteine ​​​​ka kakaretso e bolokehile ebile e mamelloa hantle, e nang le litla-morao tse fokolang. Leha ho le joalo, joalo ka tlatsetso efe kapa efe, ho eletsoa ho buisana le setsebi sa tlhokomelo ea bophelo pele u qala tlatsetso ea N-Acetylcysteine, haholo-holo ho batho ba nang le maemo a tlase a bongaka kapa ba noang meriana.

Qetellong, N-Acetylcysteine ​​phofo ke tlatsetso e matla e fanang ka melemo e mengata bakeng sa bophelo bo botle ba ho hema. Lintho tsa eona tsa antioxidant, mucolytic, le anti-inflammatory li sebetsa ka mokhoa o ts'oanang ho ts'ehetsa mokhoa oa ho phefumoloha le ho fokotsa tšenyo e bakiloeng ke khatello ea oxidative le ho ruruha. Le hoja lipatlisiso tse eketsehileng li hlokahala ho utloisisa ka botlalo tekanyo ea matla a eona a phekolo, N-Acetylcysteine ​​​​e na le tšepiso e le motsoako oa tlhaho le o sebetsang tsamaisong ea maemo a sa tšoaneng a phefumoloho.