Ectoinee boetse e bitsoa tetrahydromethylpyrimidinecarboxylic acid. Ectoin e sireletsa libaktheria tsa halophilic kotsing. E na le mesebetsi e 'meli e meholo: 1) Moisturizing: Ke ntho ea bohlokoa bakeng sa ho boloka tekanyo ea khatello ea osmotic. Sebopeho sa eona se ikhethang sa limolek'hule se na le matla a matla a ho kopanya molek'hule ea metsi, e ka etsang lisele Metsi a sa lefelloeng a hlophisitsoe 'me ke moisturizer e babatsehang ea tlhaho. 2) Ho lokisa: Ectoin e khona ho hanela tšenyo ea mahlaseli a kotsi letlalong le ho lokisa tšenyo ea DNA ea sele e bakiloeng ke mahlaseli a kotsi.
Motsoako oa lik'hemik'hale oa Ectoine ke 2-methyl-1,4,5,6,-ectoine-4-carboxylic acid, e tsejoang hape e le ectoine, e leng mofuta o mocha oa peptide e qhibilihang ka metsing e fumanoeng ka 1985. Li-derivatives tsa Zwitterionic amino acid. Ka 1985, Galinski o ile a qala ho khetholla le ho khetholla ectoine ho libaktheria tsa halophilic ka nuclear magnetic resonance le mass spectrometry. Tlas'a letsoai le lengata, Ectoine e sebetsa e le khatello ea osmotic e lefang solute 'me e bokella ka bongata libaktheria tse ling tsa halophilic ho hanela liphetoho khatellong e phahameng ea osmotic ea tikoloho e kantle.
Ho sebetsa hantle le karolo
Ectoineke setlolo se sebetsang sa tlhaho le se sebetsang. Hobane e na le mefuta e mengata ea ts'ireletso ea lisele, e ka sebelisoa ka mefuta e fapaneng ea litlolo tse nang le mesebetsi e fapaneng. Ectoine e na le moisturizing, antioxidant, tšireletso ea lifoto, tšireletso ea letsatsi le mesebetsi e meng. Lintho tse ntle tsa mongobo: Ho lokisa letlalo ka Ectoine ho ka fokotsa tšenyo ea letlalo e bakoang ke ho felloa ke metsi; molek'hule e le 'ngoe ea Ectoine e ka kopanya limolek'hule tse 'nè kapa tse hlano tsa metsi' me ea hlophisa metsi a sa lefelloeng liseleng. Ha e bapisoa le glycerin, ectoine e na le mongobo o eketsehileng letlalong. Lintlha tse amehang li bontša hore Ectoine e ka tsoela pele ho ntlafatsa matla a letlalo a mongobo le ho boloka metsi nakong ea kopo.
Matla a letlalo a ho boloka metsi a ke ke a fokotseha hang ka mor'a ho khaotsa ho sebelisa. Ka mor'a beke ea ho khaotsa, matla a letlalo a ho tšoara metsi a ntse a phahame ho feta a sehlopha sa taolo. Antioxidant e sebetsang hantle: Liteko tsa bongaka li bonts'itse hore ectoin e ka thibela ho fokola ha matla a antioxidant a lisele ka lilemo mme e na le matla a itseng a antioxidant. Lintlha tsa liteko li bonts'a hore ts'ebeliso e kopaneng ea 0.1mMEctoine, meriana ea 0.5mM le 1.5mM mannitol e ka fokotsa ho robeha ha DNA ea glial cell ka tlas'a mohloli oa leseli oa 400-800nm, ho fokotsa matla a karabelo ea oxidation ea ROS, ka hona ho fokotsa oxidation ea leseli. letlalo. kotsi. Tšireletso ea tsamaiso ea 'mele ea ho itšireletsa mafung Lisele tsa Langerhans tse ka har'a epidermis li phetha karolo ea bohlokoa tsamaisong ea 'mele ea ho itšireletsa mafung, empa li khona ho mamella khatello ea ultraviolet haholo.
Ectoinee ka thibela palo ea lisele tsa Langerhans ho fokotsoa ke mahlaseli a ultraviolet, e leng ho lumellang tsamaiso ea 'mele ea ho itšireletsa mafung ea letlalo hore e lule e sebetsa hantle. Tšireletso ho tloha ho photoaging le tšireletso ea letsatsi Botsofali ba letlalo hase feela phello ea ho feta ha nako, empa e 'ngoe ea lintlha tsa bohlokoa tsa ka ntle ke mahlaseli a ultraviolet, haholo-holo UVA (320-400nm). Sehlopheng sohle sa ultraviolet, UVA e na le leqhubu le lelelele ka ho fetisisa le matla a tlaase ka ho fetisisa. Leha ho le joalo, ho fapana le UVB, phetoho ea litaba tsa UVA khanyeng ea letsatsi ha e amehe haholo ke latitude, nako, boemo ba leholimo le nako ea selemo.
Ka hona, tlhahiso ea UVA e amoheloang letsatsi le leng le le leng le selemo le selemo Litekanyo li batla li tsitsitse 'me li tsoela pele ho bokellana ka bongata bophelong bohle ba rona.
Tšebeliso:
Ecdoine e na le mesebetsi ea ho kolobisa le ho lokisa 'me e sebelisoa haholo lefapheng la lihlahisoa tsa tlhokomelo ea letlalo ho ntlafatsa molumo oa letlalo.
Mokhoa oa ho lokisetsa
Hajoale, Ectoine e ntšitsoe haholo mefuteng ea halophile. Theknoloji ea indasteri ea ho sebelisa halobacteria ho hlahisa ectoine e thehiloe. Theknoloji ena e sebelisa glycerol e ngata e le mohloli oa carbon 'me e sebelisa mokhoa ona o bitsoa "bacterial milking". Ts'ebetso ea "bacterial milking" ke hore mefuta ea baktheria ea halophilic e hola le ho ikatisa ka bongata bo bongata (joalo ka 100g/L) mokelikeli oa letsoai. Ectoine e sebetsa e le solute ea matšeliso ea khatello ea osmotic mme e bokellana ka bongata ho libaktheria tse ling tsa halophilic ho hanela tikoloho ea kantle.
Liphetoho khatellong e phahameng ea osmotic; ha mahloriso a sele a fihla boemong bo phahameng ka ho fetisisa, letsoai le theoha ka tšohanyetso ho tloha sebakeng se phahameng (joaloka 100g / L) ho ea ho tse fokolang (tse kang 20g / L). Ha e susumetsoa ke hypotonicity, libaktheria li ka hang-hang Ectoine e bokelletsoeng liseleng e lokolloa ho ea lefats'eng le ka ntle ho qoba ho atolosoa ha sele kapa ho senyeha ka lebaka la ho fokotseha ha khatello ea osmotic ea tikoloho. Qetellong, Ectoine e ka hloekisoa le ho feta ka ho sefa, crystallization le mahlale a mang ho fumana Ectoine. Lingoliloeng li bontša hore ho sebelisoa mokhoa o ka holimo, hoo e ka bang 2g Ectoine e ka fumanoa ka litara e le 'ngoe ea mokelikeli oa setso ka letsatsi. Bioactive Ectoine ke ntho ea tlhaho e sireletsang lisele, e tsoang ho amino acid e hlahisoang ke libaktheria tse phelang maemong a thata haholo a tikoloho. Ectoine e sebelisoa e le solute e lumellanang le osmoregulation ho eketsa hydration holim'a letlalo le ho tsitsisa lipid layer, 'me hangata e sebelisoa tlhokomelong ea letlalo. Ectoine e na le boemo bo botle ba polokeho 'me e ka sebelisoa ho ithuta ho kula ha rhinitis.
Ectoin e sebetsa hantle le lisebelisoa life tse ling?
Nahana ka ectoin joalo ka UN ea metsoako ea skincare — e bapala hantle le hoo e ka bang mesebetsi eohle e meng. Dr. King o re: "Ho monate ho e kopanya le metsoako e ka 'nang ea halefisa joaloka retinoids le hydroxy acids," ho bolela Dr. King, kaha ectoin's hydrating le tšireletso e ka thusa ho loantša le ho fokotsa monyetla oa ho teneha leha e le ofe kapa bofubelu.2"Melemo ea ectoin e ka matlafatsoa ke metsoako e nang le thepa ea humectant, joalo ka hyaluronic acid le glycerin, kapa metsoako e thusang ho matlafatsa lepheko la letlalo, joalo ka liceramide le peptide. Tsena li sebelisana hantle ho sireletsa letlalo le ho matlafatsa metsi,” ho phaella Dr. Palm.
Ke Mang ea Lokelang ho Nahana ka ho Sebelisa Ectoin?
Litaba ke tsena tse monate-bobeli ba dermatologists re fana ka lintlha ka ho hatisa taba ea hore ectoin hangata e mamelloa hantle ke mang kapa mang le motho e mong le e mong, ho sa tsotelehe mofuta oa letlalo la hao, kahoo ha ua tlameha ho imeloa kelellong ka litla-morao (le hoja e le hantle haholo. haeba u loana le letlalo le omeletseng le / kapa le tenehileng). Ha ho buuoa joalo, ho sa lumelloe ke motsoako ho ntse ho khoneha, kahoo ho molemo ho etsa tlhahlobo ea patch ka sehlahisoa sefe kapa sefe se secha sa tlhokomelo ea letlalo.
Pls ikopanye le Alisa kasales02@imaherb.combakeng sa lintlha tsa theko le COA
Nako ea poso: Mar-29-2024
