Benfotiamine ke tlatsetso ea lijo e fetoloang 'meleng ho thiamine (vithamine B1). Thiamine e thusa 'mele oa hau ho fetola limatlafatsi matla' me e bohlokoa bakeng sa ts'ebetso ea boko. Batho ba bang ba sebelisa benfotiamine ho phahamisa maemo a thiamine hobane e nkoa e le bioavailable haholo.Sena se bolela hore e fihla maling ka potlako 'me e hlahisa maemo a phahameng a thiamine' meleng.
Hobane e na le antioxidant le anti-inflammatory properties, benfotiamine e ka boela ea thusa bakeng sa lefu la tsoekere la neuropathy (bohloko ba methapo) le lefu la Alzheimer.
Melemo ea bophelo bo botle ea benfotiamine
1. Diabetes neuropathy
Phekolo ea Benfotiamine e bonahala e le leano le ka sebelisoang ho thibela lefu la tsoekere, e leng bothata bo matla ba lefu la tsoekere, le amanang le kotsi e kholo ea lefu la pelo le lefu. Maemo a phahameng a tsoekere a lebisa ho bokelleng ha triosephosphates; sena se lebisa ho se sebetseng ha lik'hemik'hale le qetellong ho nts'etsopele ea lefu la tsoekere la nephropathy.
Boithuto ba pele ho likhoto bo bontšitse hore benfotiamine e thibela ho bokellana ha triosephosphates ho lefu la tsoekere mme ka hona e thibela nts'etsopele ea nephropathy.
2. Ntlafatso ea kelello ho lefu la Alzheimer
Liphuputso tsa preclinical li bonts'itse hore benfotiamine e fana ka litlamorao tse ntle ho ho senyeha ha kelello ho lefu la Alzheimer's. Benfotiamine e bontšitsoe ho fokotsa ho kenngoa ha li-amyloid mefuteng ea liphoofolo tsa lefu la Alzheimer's. Leha ho le joalo, liphello tsena ha lia pakoa ho batho. Teko ea kliniki ea mohato oa II hajoale e ntse e hlahloba hore na benfotiamine e ka emisa ho theoha ha kelello ho bakuli ba nang le bokooa bo fokolang ba kelello.
3. Ho hlōla bokhoba ba tahi
Ho noa joala ho sa feleng ho amahanngoa le khaello e matla ea limatlafatsi tsa bohlokoa le livithamine. Khaello ea thiamine e amanang le bokhoba ba tahi e khetholloa ke li-syndromes tsa methapo ka lebaka la tahlehelo e tsoelang pele ea taba e tšoeu e bohareng le ea peripheral. Leha phetisetso ea thiamine e le bohlokoa ho bakuli ba nang le ts'enyo ea methapo e bohareng e bakiloeng ke joala, benfotiamine ha e so ka e sebetsa hantle ho tšelela ho tsamaiso ea methapo e bohareng ho tsoa periphery.
4. Benfotiamine bakeng sa ho tsuba
Ho tsuba ho lebisa ho ho se sebetse ha endothelial, ketsahalo ea pele ea lefu la pelo. Sena se mpefatsoa ke khatello ea oxidative le ho ruruha. Phuputsong ea pele ho litoeba, benfotiamine e fumanoe e thibela ho se sebetse ha methapo e bakoang ke nicotine. Teko e entsoeng ho baithaopi ba phetseng hantle e bontšitse hore kalafo ea nakoana e nang le benfotiamine e ka khutlisetsa tšebetso ea macrovascular ho batho ba tsubang ba phetseng hantle.
5. Tšireletso ea liphio
Lintlha tse tsoang lithutong tsa rat li fana ka maikutlo a hore benfotiamine e fana ka ts'ireletso ho lera la peritoneal le liphio tse setseng ho peritoneal dialysis le uremia. Ho latela phuputso e phatlalalitsoeng ho Journal of the American Society of Nephrology, ho eketsoa ha benfotiamine lijong ho lebisa ts'ebetsong e eketsehileng ea transketolase le ho fokotseha ha polelo ea lihlahisoa tse tsoetseng pele tsa glycation le li-receptor tsa tsona.
Thuto e entsoeng ke Ustuner et al. e hatisitsoeng ho Tissue le Cell e fumane hore tlatsetso ea benfotiamine e ka thusa ho fokotsa nephrotoxicity e bakoang ke lithibela-mafu ka ho ntlafatsa khatello ea oxidative le ho ruruha ha lisele tsa renal tubular.
6. Monyetla oa Antitumor
Liphuputso tsa in vitro li fana ka maikutlo a hore benfotiamine e ka emisa leukemia ka mochine o bitsoang paraptosis cell death. Paraptosis ke mofuta oa lefu la lisele tse hlophisitsoeng tse kenyelletsang sebopeho sa cytoplasmic vacuole. Phuputso ea setso sa lisele ke bafuputsi ba Univesithi ea Kanazawa e Japane e fumane hore benfotiamine ke moemeli ea ts'episang bakeng sa bakuli ba acute myeloid leukemia ba sa tšoaneleheng bakeng sa chemotherapy e tloaelehileng. Ba boetse ba hlokometse hore benfotiamine e bontšitse ts'ebetso ea synergistic le cytarabine, moemeli oa chemotherapeutic, ho felisa lisele tsa myeloid leukemia.
7. Antioxidant thepa
Benfotiamine hape ke antioxidant e matla e nang le thepa e thibelang ho ruruha e hlahisoang ka ho thibela prostaglandin le leukotriene synthesis.
Tekanyetso: Ke Lokela ho Nka Benfotiamine Bokae?
Kamehla buisana le mofani oa tlhokomelo ea bophelo pele u nka tlatsetso ho netefatsa hore tlatsetso le litekanyetso li loketse litlhoko tsa hau ka bomong.
Ha ho litlhahiso tsa litekanyetso tse sireletsehileng kapa tse sebetsang tse thehiloeng bakeng sa benfotiamine e le phekolo bakeng sa boemo leha e le bofe.
Lithuto tse ngata ho batho ba nang le lefu la tsoekere ba sebelisitse litekanyetso tsa 300 mg habeli ka letsatsi. Liteko tse ling li sebelisitse litekanyetso tse fihlang ho 900 mg ka letsatsi ntle le mathata a bohlokoa.
Haeba u batla ho leka li-supplement tsa benfotiamine, buisana le mofani oa tlhokomelo ea bophelo. Ba ka u tataisa mabapi le hore na ho bolokehile bakeng sa hau le ho u thusa ho fumana tekanyo e nepahetseng.
Nako ea poso: Apr-04-2023
