Li-capsules tsa semela tse sebelisoang lihlahisoa tsa rona tse entsoeng li entsoe ka hydroxypropylmethylcellulose (HPMC), e tsejoang hape e le hydroxypropylmethylcellulose. Hona joale, nakong e fetileng, ho ne ho khoneha ho thathamisa litaba tsena ka har'a leibole:
Lisebelisoa tse ling:li-capsules tsa semela (fiber ea semela le metsi)
Empa joale FDA e ile ea fetola melao ea ho ngola hore likatiba tsa meroho li thathamisitsoe e le hydroxypropyl methylcellulose kapa hydroxypropyl methylcellulose.
Ka hona, ho lokela ho hlokomeloa pele hore hydroxypropyl methylcellulose phthalate (HPMCP) ke ntho e fapaneng le HPMC e tobileng (hydroxypropyl methylcellulose kapa hydroxypropyl methylcellulose). E, lentsoe lena le tlisa phapang e khōlō.
Ho ea ka tafole e khethehileng ea moetsi oa katiba ea meroho:
HPMC ke sehlahisoa sa semela seo e leng mofuta o hloekisitsoeng oa selulose e ntšitsoeng makhasing a lehong. Ho ea ka Annex I ea EU Regulation No. 1169/2011 mabapi le ho fana ka tlhahisoleseding ea lijo ho bareki, HPMC e khetholloa e le "fiber" 'me e hlalosoa e le polymer ea lik'hemik'hale tsa metsi a carbon tse nang le likarolo tse tharo kapa ho feta tsa monomer, tse sa cheheng kapa hona ho kenngoa mala a manyane a motho.
Leha ho le joalo, mekhoa ea hajoale ea tlhahlobo ea laboratori bakeng sa fiber ea lijo, joalo ka AOAC 985.29, ha e bone HPMC ka nepo e le fiber ea lijo. Leha ho le joalo, HPMC ke polymer ea lik'habohaedreite tse jeoang, fiber ea lijo e nang le liphello tse molemo tsa 'mele, e' nileng ea amoheloa ka ho pharaletseng ke bopaki ba saense, kahoo e ka phatlalatsoa ka boithaopo.
Bakeng sa ba sa kang ba ithuta k'hemistri e ngata haholo
Cellulose ke ketane e entsoeng ka carbon, hydrogen, le oxygen, eo hangata e nang le makholo ho isa ho likete tsa liketane tsa carbon, hydrogen, le oxygen hammoho.
Hydroxyl - e bolela hore ho na le oksijene le hydrogen tse hokahaneng kae-kae ka ketane ea cellulose, ho fapana le haedrojene feela.
Propyl - ho bolela hore ho na le ketane e lehlakoreng sebakeng se itseng sa ketane, moo liathomo tse tharo tsa carbon li pota-potiloeng ke hydrogen.
Methyl - E tšoana le propyl, empa eseng lik'habone tse tharo, empa e le 'ngoe feela.
Kopanya lintho tsena tse 'ne 'me u tla fumana=hydroxypropyl methylcellulose
E le hore ke hlahlobe boitsebiso bona ka hloko le ho netefatsa hore ha ho na litaba tse hlokomolohuoang kapa tse khabisitsoeng, ke ile ka hlahloba hore na Dr. Joseph Mercola (ngaka ea 'nete e nang le sehlopha se feletseng sa bafuputsi ba nako e tletseng) o ngotse lihlooho ka hydroxypropyl methylcellulose. Che. Eaba ke sheba li-supplement tsa hae ho bona hore na li-capsules tsa hae li entsoe ka eng. E, li thathamisitsoe tlas'a 'Lisebelisoa Tse Ling: Hydroxypropylmethylcellulose'.
Kahoo ke nahana hore ka sebele re ka re ntlha ea bohlokoa ke hore hydroxypropyl methylcellulose ke fiber e thehiloeng ho limela.
Karolo e 'ngoe e atisang ho hlaha litlatsong tsa rona ke hydroxypropyl methylcellulose, eo hangata e sebelisetsoang ho etsa li-capsules.
Hydroxypropylmethylcellulose hangata e tsoa ho cellulose ea semela, e leng carbohydrate e fumanehang maboteng a lisele tsa semela. Motsoako ona o khethehileng o atisa ho sebelisoa ha ho etsoa li-capsules tsa meroho.
Hangata Hydroxypropylmethylcellulose e hlaha ka mokhoa oa hydroxypropylmethylcellulose kapa HPMC lethathamong la metsoako, e tšoanang le "phofo ea boselamose".
Ho tloha ho limela, ha e kopane le sehlahisoa, e ka etsa hore sehlahisoa se be se teteaneng, se etsa bonnete ba hore se entsoe ka mokhoa o boreleli, esita le ho etsa hore phello ea eona e tšoarelle.
E pepenene ebile e khomarela ha e kolobile, e etsa hore e be ntho e tloaelehileng liindastering tse ngata, haholo hobane e bonolo bakeng sa 'mele ea rona mme e nkoa e le botsoalle ho tikoloho.
Hydroxypropyl methylcellulose e hlahisoa joang?
Ho boloka bonolo le ho hlaka, ke tla tsebisa ka bokhutšoanyane mehato e latelang:
- Ho ntšoa ha thepa e tala: Thepa ea mantlha ea hydroxypropyl methylcellulose ke selulose ea semela, hangata e nkiloeng ho makhasi a patsi kapa lesela la k'hothone.
- Kalafo ea alkali: Phekola cellulose ka motsoako o matla oa alkaline (joalo ka sodium hydroxide) ho e fetola selulose ea alkaline.
- Methylation: Mohato ona, selulose ea alkaline e phekoloa ka methyl chloride ho hlahisa lihlopha tsa methyl holim'a limolek'hule tsa cellulose.
- Hydroxypropylation: Mona ke moo hydroxypropyl e hlahisoang teng. Methylcellulose e sebetsana le epoxy propane, e bakang khokahanyo ea lihlopha tsa hydroxypropyl.
- Tlhoekiso: Ebe u hloekisa hydroxypropyl methylcellulose e fumanoeng ho tlosa lik'hemik'hale tse sa sebetsaneng le litšila tse ling. Hangata sena se akarelletsa ho hlatsoa, ho sefa le ho omisa.
- Ho sila le granulation: Qetellong, hydroxypropyl methylcellulose e omisitsoeng e siloa hore e be phofo e ntle 'me e ka granulated ho fumana boholo bo hlokahalang bakeng sa ts'ebeliso ea eona e reriloeng.
Tekanyo ea methylation le hydroxypropylation e ka laoloa nakong ea ts'ebetso ea tlhahiso, e tla ama litšobotsi tsa solubility le viscosity ea hydroxypropylmethylcellulose e fumanoeng.
Mochine ona o lumella bahlahisi ho iketsetsa litšoaneleho tsa bona bakeng sa lits'ebetso tse ikhethileng ho fihlela litlhoko tsa lihlahisoa tse fapaneng.
Na hydroxypropyl methylcellulose e ka ba le ts'ebeliso e mengata?
E, ke motsoako o fapaneng haholo o phethang karolo liindastering tse ngata, 'me ho na le mehlala e mengata. Ha e le hantle, e ’ngoe ea tsona e ile ea boleloa qalong ea sehlooho seo.
Ha re bue ka eona ka indasteri.
- Ka indasteri ea meriana.
Matlapa a lokolloang ka nako e telele: Hydroxypropylmethylcellulose e sebelisoa litlhahlobong tsa letlapa ho laola sekhahla sa ho lokolloa ha metsoako e sebetsang ea meriana le ho netefatsa ho lokolloa ha lithethefatsi nako e telele.
Marotholi a mahlo: A sebelisoa e le meokho ea maiketsetso litokisetsong tsa mahlo ho fokotsa matšoao a mahlo a omileng.
Moemeli oa ho roala: Thepa ea eona ea ho etsa filimi e etsa hore e sebelisoe e le sesebelisoa sa ho roala matlapa le li-capsules, ho ntlafatsa botsitso le ponahalo.
- Ka indasteri ea lijo.
Thickener le stabilizer: Hydroxypropylmethylcellulose e kenngoa lijong tse fapa-fapaneng, tse kang li-sauces, li-dessert le lintho tse halikiloeng, ho finyella botsitso kapa mokhoa o lakatsehang.
Moemeli oa Vegetarian: Ke sebaka se tummeng sa gelatin lijong tsa meroho kapa lijong tsa meroho, hobane e fana ka botsitso bo ts'oanang le gel, 'me ha e na metsoako ea tlhaho ea liphoofolo.
Sekhomaretsi sa lithaele tsa ceramic le plaster: Hydroxypropylmethylcellulose e sebelisoa e le sesebelisoa sa ho boloka metsi ho netefatsa ho omisa ka mokhoa o tsitsitseng le ho ntlafatsa ts'ebetso.
- Ka litlolo.
Thickener in lotion le face cream: E fana ka sebopeho se boreleli le botsitso bakeng sa litlolo.
E boetse e na le lisebelisoa tse ling tse khethehileng.
- Tlhahiso ea enke: e sebelisoang joalo ka motenya le botsitso.
- Temo: E sebelisoa e le setlamo sa peo ea granular.
- Indasteri ea masela: e sebelisetsoang boholo ba masela ho ntlafatsa khoele nakong ea ho loha.
Lipotso tse ling tse tloaelehileng
- Na hydroxypropyl methylcellulose e ka sebelisoa ka mokhoa o sireletsehileng?
Ee, hydroxypropyl methylcellulose hangata e nkuoa e bolokehile hore e ka jeoa 'me e amohetsoe hore e sebelisoe lijong ke mekhatlo e mengata ea taolo lefatšeng ka bophara.
- Na hydroxypropyl methylcellulose e ka senyeha?
E, joalo ka motsoako oa selulose, hydroxypropylmethylcellulose e ka senyeha, e leng se e etsang hore e se ke ea silafatsa tikoloho ha e bapisoa le li-polymer tse ling tsa maiketsetso.
- Hobaneng u sebelisa hydroxypropyl methylcellulose marotholing a mahlo?
Hydroxypropylmethylcellulose e ka etsisa litšobotsi tsa meokho ea tlhaho, e fana ka lubrication le khatholoho bakeng sa mahlo a omileng le a hlabang. Lintho tsa eona tsa viscous li e thusa ho lula holim'a mahlo nako e telele ho feta metsi, e fana ka phello ea nako e telele ea liphallelo.
Nako ea poso: Oct-30-2023
