Ha ho tluoa tabeng ea bophelo bo botle le bophelo bo botle, ho fumana li-supplement tse nepahetseng ho ka etsa phapang ea lefatše. Keira o tla u joetsa ka resveratrol posong ena kajeno. Resveratrol e tumme lefatšeng ka bophara ka lebaka la Pherekano ea Sefora eo ho buisanoeng ka eona lilemong tsa bo-1990, ha ho ne ho lumeloa hore lebaka leo ka lona batho ba Fora ba jang lijo tse nang le mafura a mangata ba sa rateheng ho tšoaroa ke lefu la pelo ke hobane resveratrol e fumaneha veineng e khubelu eo ba atisang ho e noa. .
Ho tloha ka nako eo, resveratrol e 'nile ea tsoela pele ho fumanoa bakeng sa melemo ea eona ea bophelo bo botle, ho akarelletsa le antioxidant, anti-inflammatory, anticancer, le liphello tsa ts'ireletso ea pelo.
Resveratrol ke eng?
Resveratrol, motsoako o se nang flavonoid polyphenol organic compound, ke antitoxin e hlahisoang ke limela tse ngata ha e tsosoa, ka mokhoa oa lik'hemik'hale C14H12O3. Ka 1940, setsebi sa Lejapane MichioTakaoka o ile a qala ho arola resveratrol ho tsoa ho Album ea Veratrum lelapeng la lily, 'me hamorao a e fumana ho Polygonum cuspidatum lelapeng la polygonum ka 1963. E ka etsoa ka makhasi a morara le matlalo a morara' me ke motsoako oa bioactive veine le lero la morara. E monngoa habonolo ke molomo 'me e ntšoa ka har'a moroto le mantle ka mor'a metabolism. Liteko tsa in vitro le liphoofolo li bontšitse hore resveratrol e na le antioxidant, anti-inflammatory, anticancer le liphello tse sireletsang pelo.
Resveratrole ajoa haholo limela, 'me ho tloha ka 2021, e fumanoe limela tse fetang 70 ho tloha malapeng a 21, Haholo-holo, itis e fumanoang Vitis, Ampelopsis, Polygonum, Arachis, Cassia, Sophora, Veratrum, Veratrum le Eucalyptus. Limela tse tloaelehileng tse nang le resveratrol li kenyelletsa morara, knotweed, peanuts, cassia, joalo-joalo Mokhoa oa ho kopanya lik'hemik'hale oa resveratrol ka mokhoa o bonolo le o hōlileng tsebong, lihlahisoa tse phahameng tsa lihlahisoa le theko e tlaase ea tlhahiso e sebelisitsoe bakeng sa ho lokisetsa boima ba indasteri, e le hore ho fumana resveratrol ho se ke ha khoneha. nako e telele ho itshetlehile ka ho monyoa le ho arohana le dimela. The synthesis process of resveratrol haholo-holo e sebelisa Wittig reaction ho hlokomela ho kopanngoa ha mehele e 'meli ea benzene, 'me chai e ka fihla ho feta 50%.
Liphello tsa resveratrol ke life?
- Khahlanong le botsofali
Lilemong tsa morao tjena, ho fumanoe hore li-polyphenols tse ngata li na le li-anti-oxidation tse kholo le liphello tse khahlanong le mahala.
Joaloka antioxidant ea tlhaho, resveratrol e na le ho itlhoekisa ka matla le anti-lipid peroxidation, esita le ha e bapisoa le li-antioxidants tsa setso tse kang vithamine C, butylhydroxytoluene, tocopherol, resveratrol e na le phello e ntle ea antioxidant.
Resveratrole na le phello ea eona ea antioxidant haholo-holo ka ho senya kapa ho thibela li-radicals tsa mahala, ho thibela lipid peroxidation, ho laola mosebetsi oa li-enzyme tse amanang le antioxidation le mekhoa e meng.
Resveratrol e hanela botsofali bo bakoang ke lipid peroxidation e bakoang ke li-radicals tsa mahala le metabolite ea tsona. Ka nako e ts'oanang, resveratrol e tlosa li-radicals tsa mahala, e fokotsa litaba tsa H₂O₂ letlalong, e ntlafatsa mosebetsi oa ATPase, kahoo e na le phello ea ho lieha ho tsofala ha letlalo.
- Laola tsoekere e maling
Lefu la tsoekere ke lefu le sa foleng le atileng ka ho fetesisa, empa hape le ka thibeloa habonolo, empa ka lebaka la sena hangata se tlohella batho hore ba se nke habobebe, bothata ba lefu la tsoekere ke arteriosclerosis, ntle le ho eketsa haholo monyetla oa lefu la pelo, stroke, haeba e ama li-microvessels tsa liphio, e tla tsoela pele ho baka ho hloleha ha liphio, kahoo mokhoa oa ho laola tsoekere ea mali ke oa bohlokoa bophelong.
Phuputsong e nyenyane, resveratrol (150 mg letsatsi le letsatsi bakeng sa matsatsi a 30, DSM proprietary component resVida) e ntlafalitse tsoekere ea mali (ka 4.2%) le litekanyetso tsa insulin (ka 13.7%) ho batho ba batenya haholo.
- Anti-tumor, anti-cancer
Resveratrol e na le phello e kholo ea thibelo ho hepatocellular carcinoma, mofetše oa matsoele, mofetše oa mala, mofets'e oa mala, leukemia le lisele tse ling tsa tumor. Litsebi tse ling li netefalitse hore resveratrol e na le phello e hlakileng ea ho thibela lisele tsa melanoma ka mokhoa oa MTT le cytometry ea phallo.
Ho tlalehiloe hore resveratrol e ka ntlafatsa kalafo ea radiation ea mofets'e, ea bapala phello ea "1+1> 2", mme ea thibela ka nepo karolo ea lisele tsa mofetše. Empa ho fihlela joale, ka lebaka la ho rarahana ha mochine oa anti-tumor oa resveratrol, bafuputsi ha ba e-s'o fihlele tumellano ka mochine oa eona oa ketso.
- Mesebetsi e meng
Resveratrol e boetse e na le antibacterial, antioxidant, immunomodulatory, antiasthmatic le mesebetsi e meng ea likokoana-hloko. Resveratrol e batloa haholo ka lebaka la mesebetsi ea eona e fapaneng ea tlhaho.
Mokhoa oa ho ntša resveratrol?
- Mokhoa oa ho ntša limela tsa tlhaho
Resveratrol e ile ea ntšoa 'me ea hloekisoa ho tloha morara, knotweed le peanut. Theknoloji ea ho ntša lihlahisoa tse sa hloekang haholo-holo e kenyelletsa mokhoa oa ho ntša motsoako oa manyolo, mokhoa oa ho ntša alkali le mokhoa oa ho ntša enzyme, mokhoa oa microwave o thusitseng ho ntša, CO2 supercritical extract, ultrasonic assisted extraction le mekhoa e meng e mecha le eona e sebelisoa. Morero o ka sehloohong oa tlhoekiso ke ho arola resveratrol cis, trans isomer le resveratrol Xib ho tsoa ho resveratrol e tala e nkiloeng ho fumana trans-resveratrol. Mekhoa e tloaelehileng ea ho hloekisa ke chromatography, silica gel column chromatography, thin layer chromatography, high performance liquid chromatography joalo-joalo.
- Mokhoa oa ho kopanya
Ka lebaka la litaba tse tlase tsa resveratrol limela le litšenyehelo tse phahameng tsa ho ntšoa, ts'ebeliso ea mekhoa ea boenjiniere ea lik'hemik'hale, baeloji le liphatsa tsa lefutso ho fumana resveratrol e fetohile mokhoa oa bohlokoahali molemong oa nts'etsopele. Perkin reaction, Hech reaction le Witting-Hormer reaction ke mekhoa ea lik'hemik'hale e hōlileng tsebong bakeng sa motsoako oa resveratrol, ka lihlahisoa tsa 55.2%, 70% le 35.7%, ka ho latellana. Ho sebelisa theknoloji ea boenjiniere ba liphatsa tsa lefutso ho laola kapa ho ntlafatsa tsela ea biosynthesis ea resveratrol ho fumana mela ea limela tse hlahisang lihlahisoa tse ngata; Sehlahisoa sa resveratrol se ile sa eketseha ka linako tse 1.5 ~ 3.0 ka mutagenesis le mekhoa e meng.
Aogubio ke k'hamphani e sebetsanang le tlhahiso le kabo ea lintho tse sebetsang hantle tsa meriana, lisebelisoa tse tala le lihlahisoa tsa limela, ho kenyeletsoa le limatlafatsi bakeng sa tlhahiso ea li-supplement tsa batho. Re tsepamisitse maikutlo ho meriana le lihlahisoa tsa indasteri ea meriana, lijo, phepo e nepahetseng le ea litlolo, 'me re ikemiselitse ho fa bareki lisebelisoa tsa boleng bo phahameng le tse sebetsang hantle.Resveratrol ke e' ngoe ea metsoako eo re fanang ka eona ka lihlahisoa tsa limela.
NETEFALETSO EA BOLENG:
Setsi sa rona se na le laboratori e sebelisang chromatography ea morao-rao ea khase ho leka ka matla bohloeki le matla a thepa ea rona e tala; ho netefatsa hore bareki ba rona ba fumana lihlahisoa tsa boleng bo holimo ka linako tsohle.
TŠEBELETSO EA BAREKI:
Ho boloka sepheo sa rona sa ho phethahatsa Leano la Tiisetso ea Khotsofalo, sehlopha sa rona se inehetseng se lula se itokiselitse ho fa e mong le e mong oa bareki ba rona indasteri e etellang pele tšebeletso ea bareki karolong e 'ngoe le e 'ngoe ea taelo.
Haeba u batla ho tseba kapa ho reka resveratrol ea boleng bo holimo, ka kopo ikopanye le kayla.
Ikopanye le: Keira Zhang
Lengolo-tsoibila: sales06@aogubio.com
Mohala: +86 18066856327
Nako ea poso: Jan-08-2024
